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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight reduction in addition to a reduced-calorie diet and exercise.

Using two separate drugs to lose weight can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you ought to err assisting caution and allow FDA do its job and demand some research be done so that the public recognizes the side effects and dangers of the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on their own medications.

Researchers found out that participants taking this drug for any year, lost weight within one month and have kept the extra weight off through the 56 weeks in the study. Contrave is a combination in the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which might be made up of more than one active ingredient, which may make them more effective and safer.

Combo-pilling is the newest fad or also the newest into the future under scrutiny and thus it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular may be the fact that since right now there are no long term prescription weightloss pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be approved by the FDA.

Seizures are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug also can raise blood pressure levels and heart rate, and mustn't be used in people with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heart rate and must not used in patients with uncontrolled high hypertension, in addition to by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients with a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients towards the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking.


"This could be the first drug I'm aware of that targets the two appetite and reward centres inside brain," he was quoted saying.